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RESEARCH

Our research focuses on developing statistical methodologies to facilitate the analysis, integration and interpretation of high-throughput omics data. Many of our research projects center around microarrays and the next generation sequencing platforms, for understanding biological regulation in cancer and psychiatry disorders. We have developed softwares for DNA methylation and ChIP-Seq data.

WTC WELLNESS PROGRAM GENETICS RESEARCH

Our lab is involved in the Stony Brook WTC Wellness Program research projects that evaluate the extent of mental and physical illness in hundreds of 9/11 responders. We develop statistical and bioinformatics models of integrative genomics (DNA methylation and RNA-Seq) to understand genetic vulnerability and gene-environment interactions in the etiology of the post traumatic stress disorder (PTSD), major depressive disorder (MDD), lower respiratory symptoms (LRS) and prostate cancer risk among the 9/11 responders.

FUNDING: U01 (U01-OH011478) grant from CDC/NIOSH.

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LAB NEWS

June 2018: Our exposure ranking index vs DNA methylation in WTC paper is accepted by EJCP.

June 2018: Our quantitative decision making paper is accepted by JBS.

May 2018: Xu Ren passed his preliminary exam.

News Archive